More than 50 researchers and 10 technicians are attached to Centre for Epigenetics. It is organised in five research groups based in Copenhagen and Odense. The groups are working with epigenetics from different angles and perspektives.

The five group leaders are:
- Kristian Helin
- Anders H. Lund
- Ole Nørregaard Jensen
- Morten Frödin
- Klaus Hansen

Centre for Epigenetics is located at BRIC, University of Copenhagen:

Ole Maaløes Vej 5, 4th floor
DK-2200 Copenhagen N, Denmark
Phone: +45 3532 5606
Fax:    +45 3532 5669

Welcome to Centre for Epigenetics

The Centre for Epigenetics was established in the spring 2007 as a Centre of Excellence funded by The Danish National Research Foundation. The Centre brings together the distinct expertise of five research groups with the aim of unveiling basal mechanisms of epigenetic gene regulation fundamental to all eukaryotic organisms.

Central to the research is the histone code-hypothesis and the protein complexes that write, translate and erase the code. What are their biological and biochemical functions, and what role do they play in the normal development and disease?

Professor Kristian Helin (BRIC) is the director of the centre, which consists of four research groups – four of them are located at BRIC, University of Copenhagen, and one at Department of Biochemistry and Molecular Biology, University of Southern Denmark.

In GEN (Feb 2010) you can read about how findings in epigenetics could transform future cancer biology in "Insights Accrue on Epigenetc Modification".

Researchers from the Centre for Epigenetics and BRIC publishes article on their significant findings on the regulation of embryonic stem cell differentiation in Nature, January 2010.

The results demonstrate that the Jumonji- and ARID-domain-containing protein JARID2 is essential for the binding of the Polycomb Group (PcG) proteins to target genes and, consistent with this, for the proper differentiation of embryonic stem cells and normal development and differentiation.

In GEN (Feb 2010) you can read about how findings in epigenetics could transform our understanding of cancer biology and get insigt of how some the field's most outstanding researchers, including Kristian Helin, view the impact of their findings.

Read the article: Insights Accrue on Epigenetc Modification

Put shortly, epigenetics is defined as hereditary traits that are not dependent on changes in the DNA sequence.
Here is a little longer explanation…

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